ChemicalBook > CAS DataBase List > FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
- Product Name
- FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
- CAS No.
- 97612-24-3
- Chemical Name
- FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
- Synonyms
- Eticlopride HCl;Eticlopride hydrochl;S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE;(2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride;3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride;Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1);FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
- CBNumber
- CB42130556
- Molecular Formula
- C17H26Cl2N2O3
- Formula Weight
- 377.31
- MOL File
- 97612-24-3.mol
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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Property
- Melting point:
- 144-146 °C(Solv: acetone (67-64-1))
- storage temp.
- Desiccate at RT
- solubility
- H2O: soluble >10mg/mL
- form
- powder
- color
- off-white
- optical activity
- [α]27/D 7.2°, c = 0.3 in methanol(lit.)
- Water Solubility
- Soluble to 100 mM in water
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Safety
- WGK Germany
- 3
- RTECS
- CV2450000
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- E101
- Product name
- S-(?)-Eticlopride hydrochloride
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $178
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- E101
- Product name
- S-(?)-Eticlopride hydrochloride
- Purity
- ≥98% (HPLC), powder
- Packaging
- 100mg
- Price
- $476
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29112
- Product name
- Eticlopride (hydrochloride)
- Packaging
- 5mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29112
- Product name
- Eticlopride (hydrochloride)
- Packaging
- 10mg
- Price
- $121
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29112
- Product name
- Eticlopride (hydrochloride)
- Packaging
- 25mg
- Price
- $252
- Updated
- 2024/03/01
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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Chemical Properties,Usage,Production
Uses
Dopamine receptor antagonist
Uses
S-(?)-Eticlopride hydrochloride has been used in astrocyte-neuron coculture and functional magnetic resonance imaging (fMRI) experiments.
Biological Activity
Selective dopamine D 2 /D 3 receptor antagonist (K i values are 0.50 and 0.16 nM respectively). Antipsychotic.
Biochem/physiol Actions
Potent and selective D2 dopamine receptor antagonist. Eticlopride is highly specific for DAD2?receptors than pimozide or haloperidol. The gene encoding the D2 dopamine receptor (DRD2) is linked with a several disorders including Parkinson′s disease, schizophrenia, and susceptibility to alcoholism.
storage
room temperature (desiccate)
FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Suppliers
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- 888-539-0666
- Fax
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- United States
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- +1-833-552-7181
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- United States
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- +1-781-999-5354
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- United States
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